Partnership to Fight HIV/AIDS in South Africa

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Map of South Africa

The United States is proud to be supporting South Africa’s leadership in the fight against HIV/AIDS. On December 14, 2010, U.S. Secretary of State Hillary Rodham Clinton joined South African Minister Maite Nkoana-Mashabane to sign a Partnership Framework, which provides a five-year joint strategic plan to fight HIV/AIDS. PEPFAR’s financial and technical assistance will support the leadership and implementation capacity of the South African Government and civil society, improving the effectiveness, efficiency, and sustainability of the response. By the end of the five-year period, the collaboration is expected to result in greater prevention efforts and expanded services for HIV and TB, and in a strengthened national health system.

HIV/AIDS in South Africa

  • Adult (15–49) HIV prevalence, 2009: 17.8%1
  • Estimated adults and children (ages 0-49) living with HIV, 2009: 5,600,0001
  • HIV-related deaths, 2009: 310,0001
  • Orphans due to AIDS, 2009: 1,900,0001
  • Estimated number of people needing antiretroviral therapy based on WHO 2010 guidelines, 2009: 2,600,0004
  • Estimated percentage of pregnant women living with HIV who received antiretrovirals for PMTCT, 2009: 88%2

Saving Lives: PEPFAR Program Results

Progress achieved in South Africa through direct PEPFAR support during fiscal year (FY) 2010:3

  • 917,700 individuals receiving antiretroviral treatment
  • 2,160,300 HIV-positive individuals who received care and support (including TB/HIV)
  • 386,400 orphans and vulnerable children receiving support
  • 682,400 pregnant women with known HIV status received services to prevent mother-to-child transmission of HIV (PMTCT)
  • 207,100 HIV-positive pregnant women received antiretroviral prophylaxis for PMTCT
  • 39,349 estimated infant HIV infections averted
  • 5,034,200 individuals received counseling and testing

U.S. Support for South Africa

PEPFAR Bilateral Funding for South Africa (US$ in millions)

FY 2004

FY 2005

FY 2006

FY 2007

FY 2008

FY 2009

FY 2010

FY 2011


TOTAL FY 2004-2011











South Africa has also benefitted from grants from the Global Fund to Fight AIDS, Tuberculosis and Malaria, to which the U.S. is the largest single contributor. For more information on grants from the Global Fund, visit

1 UNAIDS, Report on the global AIDS epidemic, 2010.

2 WHO, UNAIDS and UNICEF, Towards universal access: Scaling up priority HIV/AIDS interventions in the health sector, 2010.

3 PEPFAR defines direct support as data that captures the number of individuals receiving prevention, care, and treatment services through service delivery sites or providers directly supported by U.S. Government (USG) interventions or activities at the point of service delivery. An intervention or activity is considered to be direct support if it can be associated with counts of uniquely identified individuals receiving prevention, care, or treatment services at a unique program or service delivery point benefiting from the intervention or activity.

4WHO, UNAIDS, and UNICEF, Towards universal access: Scaling up priority HIV/AIDS interventions in the health sector, 2010. U.S. Government interagency website managed by the Office of U.S. Global AIDS Coordinator
and the Bureau of Public Affairs, U.S. State Department.
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