HIV-associated Malignancies in Malawi

Linked: HIV-Associated Malignancies in Malawi

Contact Principal Investigator: KUMWENDA, JOHNSTONE JONNY, jkumwenda@jhu.medcol.mw

Project Title: LINKED: HIV-ASSOCIATED MALIGNANCIES IN MALAWI

 Awardee Organization: UNIVERSITY OF MALAWI

 Partner Organizations: Johns Hopkins University, University of North Carolina—Chapel Hill, University of Cape Town

The prevalence of HIV remains high in Malawi; the national estimate among adults is approximately 11% but the prevalence among reproductive age women is much higher- approximately 18%. The expanding antiretroviral treatment services provide an opportunity for longer survival of HIV infected individuals. In Malawi, as well as in most sub-Saharan Africa, adequate registries do not exist to document and monitor complications of HIV. An important complication is HIV-associated cancers (malignancies), which have been reported to be increasing. However, we do not know the cancer burden, and consequently are not able to assess the impact of the HIV epidemic on the rates of these cancers. The main deficiencies are weak or non-existent surveillance systems and poor classification of diseases, especially cancers (including HIV associated malignancies). Major underlying factors contributing to these limitations are inadequately trained personnel coupled with poor infrastructure. Therefore, building capacity to establish better diagnosis, of the main cancers, surveillance of all cancers and population-based research on cancers in settings such as Malawi where resources are limited is important. In this research training program, we intend to train a diverse group of Malawian scientists and establish histopathological diagnostic services at two referral hospitals in Malawi. . We will target multiple priority areas of training to improve diagnostic capabilities. We intend to train physicians, technologists, epidemiologists, basic scientists and others to acquire the needed skills. The training will be done in diverse places including Malawi, the USA, South Africa, Uganda and Zambia. , The duration of training will be variable including formal/long term (masters in public health and pathology), medium term and short term. The participating program faculty is diverse with experience in multiple disciplines. This training program is a preparatory one for possible future programmatic award to improve health care in Malawi. The training program will be highly integrated with our ongoing HIV research working in Malawi at the Blantyre and Lilongwe research sites.


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