Since its inception in 2003, the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) has received strong bipartisan support in Congress and through administrations, including two reauthorizations with significant majorities. The United States is unquestionably the world’s leader in responding to the global HIV/AIDS crisis.
Through PEPFAR, the U.S. has supported a world safer and more secure from infectious disease threats. We have demonstrably strengthened the global capacity to prevent, detect, and respond to new and existing risks – which ultimately enhances global health security and protects America’s borders.
Originally conceived as a compassionate effort to deliver lifesaving services in countries hardest hit by HIV/AIDS, PEPFAR is now also undertaking the challenge of controlling the pandemic. It is the iconic brand of U.S. government engagement in health, development, security, and diplomacy, unparalleled in its capacity to deliver clear, measurable, and transformative results and impact.
Working in over 50 countries, PEPFAR has transformed the global HIV/AIDS response. We support more than 14 million people with lifesaving antiretroviral treatment. This is compared with the only 50,000 people who were on treatment in sub-Saharan Africa when PEPFAR began.
For the first time, the latest PEPFAR data also show significant declines in new HIV diagnoses among adolescent girls and young women. In the 10 African countries (63 districts) implementing PEPFAR’s pioneering DREAMS (Determined, Resilient, Empowered, AIDS-free, Mentored, and Safe) public-private partnership, the majority (65 percent) of the highest-HIV-burden communities or districts achieved greater than a 25-40 percent decline in new HIV diagnoses among young women. Importantly, new diagnoses declined in nearly all DREAMS intervention districts.
With PEPFAR support, more than 2.2 million babies have been born HIV-free to pregnant women living with HIV and their mothers have been kept healthy and alive to protect and nurture them. PEPFAR also provides assistance to more than 6.4 million orphans, vulnerable children, and their caregivers.
PEPFAR continues to expand our impact by using data to drive accountability, find efficiencies, increase transparency, and leverage partnerships, including with the private sector. These efforts have made PEPFAR a model for development programs everywhere.
Controlling the HIV/AIDS Epidemic
PEPFAR’s Population-based Health Impact Assessments show that five countries – Lesotho, Malawi, Swaziland, Zambia, and Zimbabwe – are approaching control of their epidemics. Under the PEPFAR Strategy for Accelerating HIV/AIDS Epidemic Control (2017-2020), the program is poised to help control the epidemic in up to 13 high-HIV-burden countries by 2020 and reduce the future costs required to sustain an effective HIV/AIDS response.
PEPFAR's Interagency Model
PEPFAR is led and managed by the U.S. Department of State's Office of the U.S. Global AIDS Coordinator and Health Diplomacy and implemented by seven U.S. government departments and agencies, leveraging the power of a whole-of-government approach to controlling the HIV/AIDS epidemic.
Department of State
U.S. Agency for International
Department of Health and
Department of Defense
Department of Commerce